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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC3
All Species:
27.58
Human Site:
S1085
Identified Species:
43.33
UniProt:
Q9UQE7
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQE7
NP_005436.1
1217
141542
S1085
E
R
G
S
G
S
Q
S
S
V
P
S
V
D
Q
Chimpanzee
Pan troglodytes
XP_508031
1374
158072
S1242
E
R
G
S
G
S
Q
S
S
V
P
S
V
D
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851818
1228
142683
S1096
E
R
G
S
G
S
Q
S
S
V
P
S
V
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9CW03
1217
141537
S1085
E
R
G
S
G
S
Q
S
S
V
P
S
V
D
Q
Rat
Rattus norvegicus
P97690
1191
138430
K1052
Q
K
L
V
P
G
A
K
A
T
L
V
M
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512851
1238
143475
S1106
E
R
G
S
G
S
Q
S
S
V
P
S
V
D
Q
Chicken
Gallus gallus
Q90988
1189
134923
M1055
L
L
P
G
A
K
A
M
L
V
P
S
K
K
Q
Frog
Xenopus laevis
O93309
1209
140704
S1077
E
G
E
G
S
T
Q
S
S
V
P
S
V
D
Q
Zebra Danio
Brachydanio rerio
NP_999854
1216
141517
S1085
R
A
S
S
S
Q
S
S
V
P
S
V
D
Q
F
Tiger Blowfish
Takifugu rubipres
NP_001027798
1217
141541
S1085
E
R
G
S
S
S
Q
S
S
V
P
S
V
D
Q
Fruit Fly
Dros. melanogaster
NP_523374
1200
140018
K1068
N
E
G
D
E
M
E
K
E
V
E
N
S
D
A
Honey Bee
Apis mellifera
XP_393700
1202
139436
P1070
D
K
G
D
D
T
T
P
E
S
A
D
S
D
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202053
792
92535
E668
R
L
S
N
Q
E
Q
E
Y
K
E
L
R
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SN90
1171
132296
S1038
K
V
N
Q
D
F
G
S
I
F
S
T
L
L
P
Baker's Yeast
Sacchar. cerevisiae
P47037
1230
141318
G1097
E
S
N
E
S
Q
N
G
K
D
S
E
I
M
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
N.A.
99
N.A.
99.9
97.2
N.A.
97.5
23.3
95.8
95.1
94.9
53.4
55.4
N.A.
40.1
Protein Similarity:
100
88.5
N.A.
99
N.A.
100
97.4
N.A.
98
46.5
97.6
97.5
97.3
73.2
72.9
N.A.
53.9
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
100
26.6
66.6
13.3
93.3
20
13.3
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
33.3
N.A.
100
26.6
73.3
13.3
93.3
33.3
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47
57.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
7
0
14
0
7
0
7
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
14
14
0
0
0
0
7
0
7
7
67
0
% D
% Glu:
54
7
7
7
7
7
7
7
14
0
14
7
0
0
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
7
% F
% Gly:
0
7
54
14
34
7
7
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% I
% Lys:
7
14
0
0
0
7
0
14
7
7
0
0
7
14
14
% K
% Leu:
7
14
7
0
0
0
0
0
7
0
7
7
7
7
0
% L
% Met:
0
0
0
0
0
7
0
7
0
0
0
0
7
7
0
% M
% Asn:
7
0
14
7
0
0
7
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
7
0
7
0
0
7
0
7
54
0
0
0
7
% P
% Gln:
7
0
0
7
7
14
54
0
0
0
0
0
0
7
54
% Q
% Arg:
14
40
0
0
0
0
0
0
0
0
0
0
7
0
7
% R
% Ser:
0
7
14
47
27
40
7
60
47
7
20
54
14
0
0
% S
% Thr:
0
0
0
0
0
14
7
0
0
7
0
7
0
0
0
% T
% Val:
0
7
0
7
0
0
0
0
7
60
0
14
47
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _